中島 亘　研究業績（発表論文）一覧

• Nakamura Y., Nakashima K., Kano R., Watanabe S., Hasegawa A. (2002) Characterization of a monoclonal antibody against desmoplakin 1 for use in dogs. Vet Dermatol 13:165-167.

• Ohno K., Konishi S., Kobayashi S., Nakashima K., Setoguchi A., Fujino Y., Nakayama H., Tsujimoto H. (2006) Prognostic factors associated with survival in dogs with lymphocytic-plasmacytic enteritis. J Vet Med Sci 68:929-933.

• Ohno K., Yokoyama Y., Nakashima K., Setoguchi A., Fujino Y., Tsujimoto H. (2006) C-reactive protein concentration in canine idiopathic polyarthritis. J Vet Med Sci 68:1275-1279.

• Kobayashi S., Ohno K., Uetsuka K., Nakashima K., Setoguchi A., Fujino Y., Tsujimoto H. (2007) Measurement of intestinal mucosal permeability in dogs with lymphocytic-plasmacytic enteritis. J Vet Med Sci 69:745-749.

• Nakamura M., Takahashi M., Ohno K., Koshino A., Nakashima K., Setoguchi A., Fujino Y., Tsujimoto H. (2008) C-reactive protein concentration in dogs with various diseases. J Vet Med Sci. 70:127-131.

• Takeuchi Y., Matsuura S., Fujino Y., Nakajima M., Takahashi M., Nakashima K., Sakai Y., Uetsuka K., Ohno K., Nakayama H., Tsujimoto H. (2008) Hypereosinophilic syndrome in two cats. J Vet Med Sci 70:1085-1089.

• Kanemoto H., Ohno K., Nakashima K., Takahashi M., Fujino Y., Tsujimoto H. (2008) Vascular and Kupffer imaging of canine liver and spleen using the new contrast agent Sonazoid. J Vet Med Sci 70:1265-1268.

• Kanemoto H., Ohno K., Nakashima K., Takahashi M., Fujino Y., Nishimura R., Tsujimoto H. (2009) Characterization of canine focal liver lesions with contrast-enhanced ultrasound using a novel contrast agent-sonazoid. Vet Radiol Ultrasound 50:188-194.

• Kanemoto H., Ohno K., Sakai M., Nakashima K., Takahashi M., Fujino Y., Tsujimoto H. (2009) Blood hyaluronic acid as a marker for canine cirrhosis. J Vet Med Sci 71:1251-1254.

• Fukushima K., Ohno K., Koshino-Goto Y., Uchida K., Nomura K., Takahashi M., Nakashima K., Fujino Y., Tsujimoto H. (2009) Sensitivity for the detection of a clonally rearranged antigen receptor gene in endoscopically obtained biopsy specimens from canine alimentary lymphoma. J Vet Med Sci 71:1673-1676.

• Ishihara M., Fujino Y., Setoguchi A., Takahashi M., Nakashima K., Ohno K., Tsujimoto H. (2010) Evaluation of prognostic factors and establishment of a prognostic scoring system for canine primary immune-mediated hemolytic anemia. J Vet Med Sci 72:465-470.

• Ito T., Uchida K., Nakamura M., Nakashima K., Suzuki K., Nakayama H. (2010) Fibrinoid leukodystrophy (Alexander's disease-like disorder) in a young adult French bulldog. J Vet Med Sci 72:1387-1390.

• Ohmi A., Ohno K., Uchida K., Nakayama H., Koshino-Goto Y., Fukushima K., Takahashi M., Nakashima K., Fujino Y., Tsujimoto H. (2010) A retrospective study in 21 Shiba dogs with chronic enteropathy. J Vet Med Sci 73:1-5.

• Takeuchi Y., Iizuka H., Kanemitsu H., Fujino Y., Nakashima K., Uchida K., Ohno K., Nakayama H., Tsujimoto H. (2010) Myeloma-related disorder with leukaemic progression in a cat. J Feline Med Surg 12:982-987.

• Kanemoto H., Ohno K., Sakai M., Nakashima K., Takahashi M., Fujino Y., Tsujimoto H. (2011) Expression of fibrosis-related genes in canine chronic hepatitis. Vet Pathol 48:839-845.

• Osumi T., Ohno K., Kanemoto H., Nakashima K., Uchida K., Karasawa A., Fujino Y., Tsujimoto H. (2011) A case of recovery from canine destructive cholangitis in a Miniature Dachshund. J Vet Med Sci 73:937-939.

• Tsukamoto A., Ohno K., Tsukagoshi T., Maeda S., Nakashima K., Fukushima K., Fujino Y., Tsujimoto H. (2011) Real-time ultrasonographic evaluation of canine gastric motility in the postprandial state. J Vet Med Sci 73:1133-1138.

• Ishida A., Ohno K., Fukushima K., Nakashima K., Takahashi M., Goto-Koshino Y., Fujino Y., Tsujimoto H. (2011) Plasma high-mobility group box 1 (HMGB1) in dogs with various diseases: comparison with C-reactive protein. J Vet Med Sci 73:1127-1132.

• Tsukamoto A., Ohno K., Maeda S., Nakashima K., Fukushima K., Fujino Y., Tsujimoto H. (2011) Prokinetic effect of the 5-HT4R agonist mosapride on canine gastric motility. J Vet Med Sci 73:1635-1637.

• Maeda S., Ohno K., Nakamura K., Uchida K., Nakashima K., Fukushima K., Tsukamoto A., Goto-Koshino Y., Fujino Y., Tsujimoto H. (2011) Quantification of chemokine and chemokine receptor gene expression in duodenal mucosa of dogs with inflammatory bowel disease. Vet Immunol Immunopathol 144:290-298.

• Ohmi A., Tsukamoto A., Ohno K., Uchida K., Nishimura R., Fukushima K., Takahashi M., Nakashima K., Fujino Y., Tsujimoto H. (2012) A retrospective study of inflammatory colorectal polyps in miniature dachshunds. J Vet Med Sci 74:59-64.

• Tsukagoshi T., Ohno K., Tsukamoto A., Fukushima K., Takahashi M., Nakashima K., Fujino Y., Tsujimoto H. (2012) Decreased gallbladder emptying in dogs with biliary sludge or gallbladder mucocele. Vet Radiol Ultrasound 53:84-91.

• Tsukamoto A., Ohno K., Irie M., Ohmi A., Maeda S., Nakashima K., Fukushima K., Fujino Y., Uchida K., Tsujimoto H. (2012) A Case of Canine Multiple Inflammatory Colorectal Polyps Treated by Endoscopic Polypectomy and Argon Plasma Coagulation. J Vet Med Sci 74:503-506.

• Maeda S., Ohno K., Nakashima K., Fukushima K., Tsukamoto A., Suzuki H., Fujiwara A., Goto-Koshino Y., Fujino Y., Tsujimoto H. (2012) Molecular cloning and characterization of canine fractalkine and its receptor CX(3)CR1. Vet Immunol Immunopathol 145:100-109.

• Maeda S., Ohno K., Tsukamoto A., Nakashima K., Fukushima K., Goto-Koshino Y., Fujino Y., Tsujimoto H. (2012) Molecular cloning and expression analysis of the canine chemokine receptor CCR9. Vet Immunol Immunopathol 145:534-539.

• Fukushima K., Kanemoto H., Ohno K., Takahashi M., Nakashima K., Fujino Y., Uchida K., Fujiwara R., Nishimura R., Tsujimoto H. (2012) CT characteristics of primary hepatic mass lesions in dogs. Vet Radiol Ultrasound 53:252-257.

• Mochizuki H., Nakamura K., Sato H., Goto-Koshino Y., Sato M., Takahashi M., Fukushima K., Nakashima K., Fujino Y., Ohno K., Uchida K., Nakayama H., Tsujimoto H. (2012) GeneScan analysis to detect clonality of T-cell receptor γ gene rearrangement in feline lymphoid neoplasms. Vet Immunol Immunopathol 145:402-409.

• Maeda S., Ohno K., Nakamura K., Uchida K., Nakashima K., Fukushima K., Tsukamoto A., Goto-Koshino Y., Fujino Y., Tsujimoto H. (2012) Mucosal imbalance of interleukin-1β and interleukin-1 receptor antagonist in canine inflammatory bowel disease. Vet J 194:66-70.

• Tsukamoto A., Ohno K., Maeda S., Nakashima K., Fukushima K., Fujino Y., Hori M., Tsujimoto H. (2012) Effect of mosapride on prednisolone-induced gastric mucosal injury and gastric-emptying disorder in dog. J Vet Med Sci 74:1103-1108.

• Maeda S., Ohno K., Nakamura K., Uchida K., Nakashima K., Fukushima K., Nakajima M., Goto-Koshino Y., Fujino Y., Tsujimoto H. (2012) Increased expression of fractalkine and its receptor CX3CR1 in canine inflammatory bowel disease and their possible role in recruitment of intraepithelial lymphocytes. Vet Immunol Immunopathol 148:226-235.

• Igarashi H., Ohno K., Ohmi A., Tsukamoto A., Nakashima K., Fujino Y., Uchida K., Tsujimoto H. (2013) Polypoid adenomas secondary to inflammatory colorectal polyps in 2 miniature dachshunds. J Vet Med Sci 75:535-538.

• Tamamoto T., Ohno K., Takahashi M., Nakashima K., Fujino Y., Tsujimoto H. (2013) Serum amyloid A as a prognostic marker in cats with various diseases. J Vet Diagn Invest 25:428-432.

• Maeda S., Ohno K., Uchida K., Nakashima K., Fukushima K.., Tsukamoto A., Nakajima M., Fujino Y., Tsujimoto H. (2013) Decreased immunoglobulin A concentrations in feces, duodenum, and peripheral blood mononuclear cells of dogs with inflammatory bowel disease. J Vet Intern Med 27:47-55.

• Kubota S., Ohno K., Tsukamoto A., Maeda S., Murata Y., Nakashima K., Fukushima K., Uchida K., Fujino Y., Tsujimoto H. (2013) Value of the 13C-urea breath test for detection of gastric Helicobacter spp. infection in dogsundergoing endoscopic examination. J Vet Med Sci 75:1049-1054.

• Takahashi M., Goto-Koshino Y., Fukushima K., Kanemoto H., Nakashima K., Fujino Y., Ohno K., Endo Y., Tsujimoto H. (2014) Phase I dose-escalation study of nimustine in tumor-bearing dogs. J Vet Med Sci 76:895-899.

• Goto-Koshino Y., Mochizuki H., Sato M., Nakashima K., Hiyoshi S., Fujiwara-Igarashi A., Maeda S., Nakamura K., Uchida K., Fujino Y., Ohno K., Tsujimoto H. (2015) Construction of a multicolor GeneScan analytical system to detect clonal rearrangements of immunoglobulin and T cell receptor genes in canine lymphoid tumors. Vet Immunol Immunopathol 165:81-87.

• Hiyoshi S., Ohno K., Uchida K., Goto-Koshino Y., Nakashima K., Fukushima K., Kanemoto H., Maeda S., Tsujimoto H. (2015) Association between lymphocyte antigen receptor gene rearrangements and histopathological evaluation in canine chronic enteropathy. Vet Immunol Immunopathol 165:138-144.

• Murata Y., Chambers J.K., Uchida K., Nakashima K., Hanafusa Y., Ikezawa M., Sugita T., Nakayama H. (2015) Mycotic aneurysm caused by Graphium species in a dog. J Vet Med Sci 77:1285-1288.

• Nakashima K., Hiyoshi S., Ohno K., Uchida K., Goto-Koshino Y., Maeda S., Mizutani N., Takeuchi A., Tsujimoto H. (2015) Prognostic factors in dogs with protein-losing enteropathy. Vet J 205:28-32.

• Fukushima K., Eguchi N., Ohno K., Kanemoto H., Takahashi M., Igarashi H., Ohmi A., Nakashima K., Tsujimoto H. (2016) Efficacy of leflunomide for treatment of refractory inflammatory colorectal polyps in 15 Miniature Dachshunds. J Vet Med Sci 78:265-269.

• Uchida E., Chambers J.K., Nakashima K., Saito T., Ohno K., Tsujimoto H., Nakayama H., Uchida K. (2016) Pathologic Features of Colorectal Inflammatory Polyps in Miniature Dachshunds. Vet Pathol 53:833-839.

• Kubota-Aizawa S., Ohno K., Kanemoto H., Nakashima K., Fukushima K., Uchida K., Chambers J.K., Goto-Koshino Y., Mimuro H., Watanabe T., Sekizaki T., Tsujimoto H. (2017) Epidemiological study on feline gastric Helicobacter spp. in Japan. J Vet Med Sci 79:876-880.

• Kubota-Aizawa S., Ohno K., Fukushima K., Kanemoto H., Nakashima K., Uchida K., Chambers J.K., Goto-Koshino Y., Watanabe T., Sekizaki T., Mimuro H., Tsujimoto H. (2017) Epidemiological study of gastric Helicobacter spp. in dogs with gastrointestinal disease in Japan and diversity of Helicobacter heilmannii sensu stricto. Vet J 225:56-62.

• Kato D., Oishi M., Ohno K., Nakashima K., Wada A., Fukumoto S.I., Morita T., Imai S., Tsuboi M., Chambers J.K., Uchida K., Tsujimoto H. (2017) The first report of the ante-mortem diagnosis of Ollulanus tricuspis infection in two dogs. J Vet Med Sci 79:e1.

• Matsumoto I., Uchida K., Nakashima K., Hiyoshi S., Chambers J.K., Tsujimoto H., Nakayama H. (2018) IgA Antibodies Against Gliadin and Tissue Transglutaminase in Dogs With Chronic Enteritis and Intestinal T-Cell Lymphoma. Vet Pathol 55:98-107.

• Matsumoto I., Uchida K., Nakashima K., Goto‐Koshino Y., Chambers J.K., Tsujimoto H., Nakayama H. (2018) Pathological features of intestinal T-cell lymphoma in Shiba dogs in Japan. Vet Comp Oncol 16:417-423.

• Saito T., Chambers J.K., Nakashima K., Uchida E., Ohno K., Tsujimoto H., Uchida K., Nakayama H. (2018) Histopathologic Features of Colorectal Adenoma and Adenocarcinoma Developing Within Inflammatory Polyps in Miniature Dachshunds. Vet Pathol 55:654-662.

• Matsumoto I., Nakashima K., Morita H., Kasahara K., Kataoka O., Uchida K. (2019) Escherichia coli-induced granulomatous colitis in a cat. JFMS Open Rep 5: 2055116919836537.

• Saito T., Nibe K., Chambers J.K., Uneyama M., Nakashima K., Ohno K., Tsujimoto H., Uchida K., Nakayama K. (2020) A histopathological study on spontaneous gastrointestinal epithelial tumors in dogs. J Toxicol Pathol 33:105-113.

• Saito T., Chambers J.K., Nakashima K., Nibe K., Ohno K., Tsujimoto H., Uchida K., Nakayama H. (2020) Immunohistochemical analysis of beta-catenin, E-cadherin and p53 in canine gastrointestinal epithelial tumors. J Vet Med Sci 82:1277-1286.

• Uneyama M., Chambers J.K., Nakashima K., Uchida K., Nakayama H. (2021) Histological Classification and Immunohistochemical Study of Feline Colorectal Epithelial Tumors. Vet Pathol 58:305-314.

• Uneyama M., Chambers J.K., Nakashima K., Uchida K. (2021) Feline pyloric and duodenal adenoma: A histological and immunohistochemical study. Vet Pathol 58:1025-1032.

• Kojima K., Chambers J.K., Nakashima K., Goto-Koshino Y., Uchida K. (2022) Immunophenotyping of intraepithelial lymphocytes in canine chronic enteropathy and intestinal T-cell lymphoma using endoscopic samples. Vet Pathol 59:227-235.

• Jaffey J.A., Kreisler R., Shumway K., Lee Y.J., Lin C.H., Durocher-Babek L.L., Seo K.W., Choi H., Nakashima K., Harada H., Kanemoto H., Lin L.S. (2022) Ultrasonographic patterns, clinical findings, and prognostic variables in dogs from Asia with gallbladder mucocele. J Vet Intern Med 36:565-575.

• Ii T., Chambers J.K., Nakashima K., Goto-Koshino .Y, Mizuno T., Uchida K. (2022) Intraepithelial cytotoxic lymphocytes are associated with a poor prognosis in feline intestinal T-cell lymphoma. Vet Pathol 59:931-939.

• Nakashima K., Matsumoto I., Goto-Koshino Y., Hiyoshi-Kanemoto S., Kojima K., Chambers J.K., Takeuchi Y., Tsujimoto H., Tomiyasu H., Uchida K. (2023) Prognostic value of increased intraepithelial lymphocytes and lymphocytic clonality in dogs with chronic enteropathy or small-cell lymphoma. Vet J 296-297:105993.

• Kojima K., Chambers J.K., Nakashima K., Uchida K. (2024) Pro-inflammatory cytokine expression and the STAT1/3 pathway in canine chronic enteropathy and intestinal T-cell lymphoma. Vet Pathol 61(3):382-392.

• Uneyama M., Chambers J.K., Fujii T., Nakashima K., Uchida K. (2024) Establishment and characterization of a novel cell line and xenotransplant mouse model derived from feline colorectal adenocarcinoma. Vet Pathol 61:190-200.

• Ii T., Chambers J.K., Nakashima K., Goto-Koshino Y., Uchida K. (2024) Intraepithelial lymphocytes are associated with epithelial injury in feline intestinal T-cell lymphoma. J Vet Med Sci 2024 86:101-110.

• Ii T., Chambers J.K., Nakashima K., Goto-Koshino Y., Uchida K. (2024) Application of automated machine learning for histological evaluation of feline endoscopic samples. J Vet Med Sci 86:160-167.

• Tomura S., Iwata T., Sugimoto T., Nakashima K., Kojima K., Uchida K., Fujita A. (2024) Choledochoduodenostomy combined with Billroth II procedure for extrahepatic biliary obstruction and duodenal perforation in a cat. JFMS Open Rep 10:20551169241246415.

• Černá P., Lopez-Jimenez C., Fukushima K., Nakashima K., Nakagawa T., Adam F., Groth A., Denning A., Israeliantz N., Gunn-Moore D.A. (2024) Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia. J Vet Intern Med 38:1005-1012.

• Nakashima K., Kojima K., Takeuchi Y., Ito M., Matsumoto I., Ushigusa T., Ohta H., Uchida K. (2025) Factors Affecting the Quality of Histopathologic Specimens Obtained via Small Intestinal Endoscopic Biopsy in Dogs and Cats. J Vet Intern Med 39(2):e70059.

• Ishikawa K., Chambers J.K., Nakashima K., Sakai T., Uchida K. (2025) Granulomatous colitis associated with Prototheca bovis infection in a young cat. J Feline Med Surg Open Rep 11(2):20551169251348548.

• Lopez-Jimenez C., Černá P., Fukushima K., Nakashima K., Nakagawa T., Adam F., Israeliantz N., Denning A., de la Puerta A. (2025) Ultrasonographic features of feline gastrointestinal eosinophilic sclerosing fibroplasia on initial presentation and during follow-up. Vet Radiol Ultrasound 66(1):e13479.

• Kojima K., Chambers J.K., Nakashima K., Nibe K., Uchida K. (2025) Immunophenotyping and Mutation Analysis of Canine Intestinal T-Cell Lymphoma: A Comparative Pathological Study of Human Enteropathy-Associated T-Cell Lymphoma. Vet Comp Oncol 23(4):567-579.

• Takahashi Y., Kato D., Uneyama M., Fujita A., Okamoto K., Nakashima K., Iwata T., Chambers J.K., Uchida K., Nishimura R., Nakagawa T. (2025) The outcomes of Swenson’s pull-through in six cats with colorectal adenocarcinoma. J Vet Med Sci 87(11):1279-1284.

• Nakamura M., Matsumoto Y., Nagata M., Yasuda K., Yonekawa K., Muramatsu S., Goshima A., Nakaki R., Yokoyama N., Nakashima K., Okumura M., Yamazaki J. (2025) Exploring DNA methylation profiles in blood samples of canine gastrointestinal lymphoma. PLoS One 20(12):e0339388.

• Ishikawa K., Chambers J.K., Kojima K., Hanamoto S., Nakashima K., Uchida K. (2026) Retrospective study of canine gastrointestinal tumors in Tokyo, Japan, 2012–2024. J Vet Med Sci 88(1):131-139.